Lipopolysaccharide (LPS)-deficient acinetobacter baumannii multivalent vaccine

The present invention relates to compositions comprising LPS-deficient inactivated cells from the genus Acinetobacter and/or their outer membrane vesicles and their use in the manufacture of medicaments, preferably vaccines, for the prevention of diseases caused by Klebsiella pneumoniae, Pseudomonas...

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Main Authors PEREZ GOMEZ ASTRID, JUAN JOSE INFANTE VENOLO, DEL MAR CORDERO ALBA MARIA, MCCONNELL MICHAEL JAMES, ROSADO ANA ISABEL RODRIGUEZ, ANDRES CORAL LUGO
Format Patent
LanguageChinese
English
Published 09.08.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compositions comprising LPS-deficient inactivated cells from the genus Acinetobacter and/or their outer membrane vesicles and their use in the manufacture of medicaments, preferably vaccines, for the prevention of diseases caused by Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli and/or Actinobacillus pleuropneumoniae and optionally Acinetobacter baumannii. 本发明涉及包含来自不动杆菌属的缺乏LPS的灭活细胞和/或其外膜囊泡的组合物，以及它们在制造用于预防由肺炎克雷伯菌、铜绿假单胞菌、大肠杆菌和/或胸膜肺炎放线杆菌以及可选的鲍曼不动杆菌引起的疾病的药物、优选疫苗中的用途。
Bibliography:Application Number: CN20228084845