Quinazoline compound and application thereof

The invention discloses a quinazoline compound and application thereof. The quinazoline compound is shown as a formula 1, has a good inhibition effect on KRAS G12D mutant protein, and has a good patent medicine prospect. # imgabs0 # 一种喹唑啉类化合物及其应用。喹唑啉类化合物如式1所示，其对KRAS G12D突变蛋白具有良好的抑制作用，有良好的成药前景。#imgab...

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Bibliographic Details
Main Authors LI DI, HUO GUOYONG, KE YING, MAO HAIBIN, ZHANG CHAOXIN, MA XING, FU YUHONG, XIA GUANGXIN, LI ZHILONG, WANG XUESONG
Format Patent
LanguageChinese
English
Published 02.08.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention discloses a quinazoline compound and application thereof. The quinazoline compound is shown as a formula 1, has a good inhibition effect on KRAS G12D mutant protein, and has a good patent medicine prospect. # imgabs0 # 一种喹唑啉类化合物及其应用。喹唑啉类化合物如式1所示，其对KRAS G12D突变蛋白具有良好的抑制作用，有良好的成药前景。#imgabs0#
Bibliography:Application Number: CN202280086284