Trans-cyclooctene conjugates

The present disclosure generally relates to trans-cyclooctene conjugates for bioorthogonal delivery of a payload to a targeted location in a subject. The compositions and methods find use in the treatment of cancer, tumor growth, and immunotherapy. 本公开总体涉及用于将有效载荷生物正交递送到受试者中的靶向位置的反式环辛烯缀合物。组合物和方法应用于癌症...

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Bibliographic Details
Main Authors ZAKARIAN, MICHAEL, MCFARLAND JESSE M, VANTOL, JOHANNES, M., M, MAHMOODI AMIN
Format Patent
LanguageChinese
English
Published 30.07.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure generally relates to trans-cyclooctene conjugates for bioorthogonal delivery of a payload to a targeted location in a subject. The compositions and methods find use in the treatment of cancer, tumor growth, and immunotherapy. 本公开总体涉及用于将有效载荷生物正交递送到受试者中的靶向位置的反式环辛烯缀合物。组合物和方法应用于癌症、肿瘤生长的治疗以及免疫疗法。
Bibliography:Application Number: CN20228083958