Methods and compositions for treating sleep apnea

• Main Authors: WOHR BENJAMIN, MILLER, LARRY, G, LUNSMAN WALTER J
• Format: Patent
• Language: Chinese; English
• Published: 26.07.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to methods and compositions for treating sleep apnea. In general, the present invention relates to pharmaceutical compositions comprising (R)-oxybutynin and a noradrenaline reuptake inhibitor (NRI), and methods of treating sleep apnea comprising administering (R)-oxybutynin and a noradrenaline reuptake inhibitor (NRI). In some embodiments, the NRI is atomoxetine. 本发明涉及用于治疗睡眠呼吸暂停的方法和组合物。总的来说，本发明涉及包括(R)-奥昔布宁和去甲肾上腺素再摄取抑制剂(NRI)的药物组合物，和包括给予(R)-奥昔布宁和去甲肾上腺素再摄取抑制剂(NRI)的治疗睡眠呼吸暂停的方法。在一些实施方案中，NRI为托莫西汀。