Compounds as CTPS1 inhibitors

The invention provides a compound. Specifically, the invention provides a compound with a structure as shown in a formula (I), or an optical isomer, a pharmaceutically acceptable salt, a prodrug, a deuterated derivative, a hydrate and a solvate of the compound. The compound can effectively inhibit C...

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Bibliographic Details
Main Authors ZHANG HANCHENG, CAI CONGCONG, ZHU SHIYA
Format Patent
LanguageChinese
English
Published 19.07.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides a compound. Specifically, the invention provides a compound with a structure as shown in a formula (I), or an optical isomer, a pharmaceutically acceptable salt, a prodrug, a deuterated derivative, a hydrate and a solvate of the compound. The compound can effectively inhibit CTPS1, and is used for treating or preventing diseases or symptoms related to activity or expression quantity of CTPS1. # imgabs0 # 本发明提供了一类化合物。具体地，本发明提供了一种如下式(I)所示结构的化合物，或其光学异构体，药学上可接受的盐，前药，氘代衍生物，水合物，溶剂合物。所述的化合物能够有效抑制CTPS1，用于治疗或预防与CTPS1的活性或表达量相关的疾病或病症。#imgabs0#
Bibliography:Application Number: CN202311017071