Esterase enzymes and uses thereof

• Main Authors: GUEROUT MARC, DUQUESNE, SOPHIE, ARNAL, GUY, TOURNIER VINCENT, MARTY ALAIN, ANDRE ISABELLE, GAVALDA SANDRA
• Format: Patent
• Language: Chinese; English
• Published: 16.07.2024
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; GENERAL PROCESSES OF COMPOUNDING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC MACROMOLECULAR COMPOUNDS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; THEIR PREPARATION OR CHEMICAL WORKING-UP; VINEGAR; WINE; WORKING-UP

The present invention relates to novel esterases, and more particularly to esterase variants having improved activity and/or improved thermal stability compared to the parent esterase of SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3 under acidic conditions, and their use for degrading polyester-containing materials, such as plastic products. The esterase of the present invention is particularly suitable for degrading polyethylene terephthalate and polyethylene terephthalate-containing materials under acidic conditions. 本发明涉及新型酯酶，更特别地涉及在酸性条件下与SEQ ID NO:1、SEQ ID NO:2或SEQ ID NO:3的亲本酯酶相比具有改善的活性和/或改善的热稳定性的酯酶变体，及其用于降解含聚酯材料如塑料产品的用途。本发明的酯酶特别适合于在酸性条件下降解聚对苯二甲酸乙二醇酯和含聚对苯二甲酸乙二醇酯的材料。