Epstein-barr virus antigen constructs

• Main Authors: CAPONE STEFANIA, FOLGORI ANTONELLA, VISEL BENJAMIN, LAHM ANDREAS
• Format: Patent
• Language: Chinese; English
• Published: 09.07.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present invention relates to an Epstein-Barr virus antigen construct. The invention provides an Epstein-Barr virus antigen polynucleotide, a polypeptide and a carrier. And an immunogenic composition comprising the same. The present invention relates to methods for treating and preventing Epstein-Barr virus infection and Epstein-Barr virus-related diseases, including the use of Epstein-Barr virus antigen constructs to produce vaccines for the treatment and prevention of Epstein-Barr virus infection and Epstein-Barr virus-related diseases, such as multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematosus. 本发明涉及爱泼斯坦-巴尔病毒抗原构建体。本发明提供了爱泼斯坦-巴尔病毒抗原多核苷酸、多肽和载体；以及包含其的免疫原性组合物。其包括使用爱泼斯坦-巴尔病毒抗原构建体来产生疫苗用于治疗和预防爱泼斯坦-巴尔病毒感染和爱泼斯坦-巴尔病毒-相关的疾病，诸如多发性硬化症、类风湿性关节炎和系统性红斑狼疮。