Dry suspension containing tigorazan and hydrotalcite as well as preparation method and application of dry suspension

• Main Authors: HUANG DAN, FENG SHOU, LIU YINGFANG, NAHUZ, ELIYA, KE XINGFA, PENG XINBING, GUO ZHIRONG, LIU HANBING, HUANG YANGBIN
• Format: Patent
• Language: Chinese; English
• Published: 09.07.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to the technical field of pharmaceutical preparations, in particular to a dry suspension containing tigorazan and hydrotalcite as well as a preparation method and application of the dry suspension. The dry suspension comprises the following components in parts by weight: 300-500 parts of hydrotalcite, 50 parts of tigorasone, 354-584 parts of a filler, 40-70 parts of a disintegrating agent, 10 parts of a stabilizer, 10 parts of a suspending aid, 1 part of a flavoring agent and 5 parts of a lubricant, and is prepared by dry granulation. According to the traditional Chinese medicine composition, gastric acid secretion is inhibited by inhibiting H < + >/K < + >-ATP enzyme through tigoran, gastric acid is neutralized through hydrotalcite, synergistic effects are achieved through combined use, related symptoms such as reflux esophagitis can be more effectively relieved, and the traditional Chinese medicine composition takes effect quickly and has small side effects. 本发明涉及药物制剂技术领域，具体涉及一种含有替戈拉生和