Anti-ILT4 and anti-PD-1 bispecific constructs

Provided herein are novel bispecific constructs against ILT4 and against PD-1, and corresponding compositions thereof. Also described herein are methods of inducing or enhancing an immune response and methods of treating cancer by administering the constructs or compositions. 本文提供新的抗ILT4和抗PD-1的双特异性构...

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Bibliographic Details
Main Authors MURPHY MICHAEL, VITALI LAURA A, KELLER TIBOR, CHEN MINGJIU, GOLDSTEIN, JOEL, O 'NEILL THOMAS
Format Patent
LanguageChinese
English
Published 05.07.2024
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided herein are novel bispecific constructs against ILT4 and against PD-1, and corresponding compositions thereof. Also described herein are methods of inducing or enhancing an immune response and methods of treating cancer by administering the constructs or compositions. 本文提供新的抗ILT4和抗PD-1的双特异性构建体，及其相应的组合物。本文还述及通过施用该构建体或组合物来诱导或增强免疫应答的方法以及治疗癌症的方法。
Bibliography:Application Number: CN202280074530