Nuclease-based RNA depletion

• Main Authors: HYDE FREDERICK W, KURSTEN SCOTT, TETSUBAYASHI ASAKO
• Format: Patent
• Language: Chinese; English
• Published: 05.07.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present disclosure relates to methods and materials for depleting unwanted RNA species from nucleic acid samples. In particular, the present disclosure describes how to remove undesired rRNA, tRNA, mRNA, or other RNA species that may interfere with the analysis, manipulation, and study of target RNA molecules in a sample. 本公开涉及用于耗尽来自核酸样本的不需要RNA种类的方法和材料。具体地，本公开描述了如何去除可能干扰样本中靶RNA分子的分析、操作和研究的不需要rRNA、tRNA、mRNA或其他RNA种类。