Hierarchical structure bionic pancreas islet, preparation method and application

The invention belongs to the technical field of biological materials, and particularly relates to a bionic pancreas islet with a hierarchical structure, a preparation method and application. The preparation method of the bionic pancreas islet with the hierarchical structure comprises the following s...

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Bibliographic Details
Main Authors LI LING, SUN JI, HUAN ZHIKUN, SHANG LUORAN, ZHAO YUANJIN, LI JINGBO
Format Patent
LanguageChinese
English
Published 25.06.2024
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Summary:The invention belongs to the technical field of biological materials, and particularly relates to a bionic pancreas islet with a hierarchical structure, a preparation method and application. The preparation method of the bionic pancreas islet with the hierarchical structure comprises the following steps: S1, sleeving a thin glass capillary tube in a thick glass capillary tube, coaxially arranging the thin glass capillary tube and the thick glass capillary tube to form an outer tube and an inner tube, and then assembling the thin glass capillary tube sleeve and the thick glass capillary tube on a glass slide by using transparent epoxy resin to form a microfluidic device; s2, injecting the biological hydrogel into the outer tube by using a micro pump, injecting a mixture of sodium carboxymethyl cellulose and islet cells into the inner tube, enabling the biological hydrogel in the outer tube and the mixture in the inner tube to form monodisperse liquid drops at an outlet of a microfluidic device under the action
Bibliography:Application Number: CN202410328979