Astaxanthin sea cucumber peptide nano dry powder capable of relieving hepatic fibrosis and preparation method of astaxanthin sea cucumber peptide nano dry powder

• Main Authors: SONG YUKUN, SU WENTAO, HUANG SHASHA, SHAO XIAOYANG, TAN MINGQIAN
• Format: Patent
• Language: Chinese; English
• Published: 25.06.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses astaxanthin sea cucumber peptide nano dry powder capable of relieving hepatic fibrosis and a preparation method of the astaxanthin sea cucumber peptide nano dry powder, and belongs to the field of food science and biological medicine. According to the invention, sea cucumber peptide, procyanidine and vanillin are used as raw materials, and the sea cucumber peptide nano-carrier is prepared based on Mannich reaction. The carrier is used for loading astaxanthin through ultrasonic homogenization based on hydrogen bond and hydrophobic interaction, an organic solvent in an emulsion system is removed through a conventional rotary evaporation separation method, and dry powder is prepared after moisture in emulsion is removed through a freeze-drying method. The nano dry powder is safe and non-toxic, can significantly promote cell proliferation, and has an improvement effect on cell oxidative stress damage caused by acrylamide and hydrogen peroxide; the traditional Chinese medicine composition h