Enhanced chimeric antigen receptors and uses thereof

Provided herein are a CD5-specific antigen-specific single-chain variable fragment (scFv), chimeric antigen receptors (CARs) comprising the scFv, immune cells expressing the CARs, and methods of use thereof in the treatment of immune diseases. 本文提供了一种CD5特异性的抗原特异性单链可变片段(scFv)，包含所述scFv的嵌合抗原受体(CARs)，表达...

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Bibliographic Details
Main Authors REZVANI KATY, ANG SONNY, SPAHR PAUL, LAU ERIC
Format Patent
LanguageChinese
English
Published 18.06.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Provided herein are a CD5-specific antigen-specific single-chain variable fragment (scFv), chimeric antigen receptors (CARs) comprising the scFv, immune cells expressing the CARs, and methods of use thereof in the treatment of immune diseases. 本文提供了一种CD5特异性的抗原特异性单链可变片段(scFv)，包含所述scFv的嵌合抗原受体(CARs)，表达所述CAR的免疫细胞及其在免疫疾病治疗中的使用方法。
Bibliography:Application Number: CN202410061631