DDR1 and DDR2 inhibitors for treatment of cancer and fibrotic diseases

The present invention relates to novel compounds of formula (I) and pharmaceutical compositions comprising the same. More specifically, the present invention relates to compounds useful as inhibitors of discoidin domain receptor 1 (DDR1) and discoidin domain receptor 2 (DDR2). The compounds are part...

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Bibliographic Details
Main Authors GUISOT, NICOLAS, E.S, JONES CLIFFORD D, BHAMRA, INDER, VARELA RODRIGUEZ ANA
Format Patent
LanguageChinese
English
Published 14.06.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel compounds of formula (I) and pharmaceutical compositions comprising the same. More specifically, the present invention relates to compounds useful as inhibitors of discoidin domain receptor 1 (DDR1) and discoidin domain receptor 2 (DDR2). The compounds are particularly useful in the treatment of cancer and fibrotic diseases. # imgabs0 # 本发明涉及式(I)的新化合物和包含该新化合物的药物组合物。更具体地，本发明涉及用作盘状结构域受体1(DDR1)和盘状结构域受体2(DDR2)的抑制剂的化合物。该化合物特别适用于治疗癌症和纤维化疾病。#imgabs0#
Bibliography:Application Number: CN202280073815