Method for catalytically synthesizing composite BX/Res biomass nano active material by rectorite

• Main Authors: QIAN JINGXIA, LYU YIJU, LIU HUAFENG, YANG JINWU, ZUO KAI, GE WENXU, ZOU ZHIMING, TIAN KEXIN, YANG YINGYING, LI HEPING, LI MINGKUN
• Format: Patent
• Language: Chinese; English
• Published: 11.06.2024
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NANOTECHNOLOGY; ORGANIC MACROMOLECULAR COMPOUNDS; PERFORMING OPERATIONS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; THEIR PREPARATION OR CHEMICAL WORKING-UP; TRANSPORTING

The invention discloses a method for catalytically synthesizing a composite BX/Res biomass nano active material by rectorite. The preparation method comprises the following steps: firstly, synthesizing a Res/BX binary grafted copolymer through free radical polymerization in a water solvent by taking a BX/Res compound as a raw material, AMPS as a grafting monomer and ammonium persulfate as an initiator; and by taking acetylated and acylated lactobionic acid as an esterifying agent, special montmorillonite as a main catalyst and 4-dimethylaminopyridine as an auxiliary catalyst, further synthesizing the BX/Res lactobionic acid ester grafted AMPS derivative in a dimethyl sulfoxide solvent. And then preparing the composite BX/Res biomass nano active material through a nano precipitation method. A brominated thiazole blue tetrazole (MTT) method is adopted to measure that the inhibition rates of the product on human liver cancer cells (BEL-7407) and human lung cancer cells (NCI-H460) are 38.52% and 33.74% respective