Method for separating and detecting piperidine and impurities thereof

• Main Authors: LI JUAN, HAN XIAOFEI, XU BIN, HU HEPING, ZHANG HAIDI
• Format: Patent
• Language: Chinese; English
• Published: 04.06.2024
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention relates to a method for separating and detecting piperidine and impurities thereof, and belongs to the technical field of quality control of piperidine. The invention provides a method for separating and detecting piperidine and impurities thereof, which adopts a gas chromatographic method, and adopts a capillary column with 14% cyanopropyl phenyl-dimethyl polysiloxane as a stationary liquid as a chromatographic column. Compared with the prior art, the method has the advantages that the separation and detection of piperidine and impurities such as n-amylamine, n-pentane, N-n-pentylpiperidine and pyridine can be simultaneously realized, and particularly, the low-content n-amylamine in piperidine can be accurately and quantitatively detected, so that not only is the quality control efficiency improved, but also the analysis cost is saved; the separation degree and the sensitivity can meet the requirements of accurate detection, and possibility is provided for more comprehensive quality control of