Application of Se-coated SiO2-DTX in preparation of product for treating prostate cancer or castration-resistant prostate cancer

• Main Authors: DAI YINING, YANG BOYU, CHANG MINGYU, LYU JINGCHENG
• Format: Patent
• Language: Chinese; English
• Published: 04.06.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the technical field of tumor resistance, and particularly relates to application of Se-coated SiO2-DTX in preparation of a product for treating prostate cancer or castration-resistant prostate cancer. The invention relates to an application of a tyrosine phosphorylation inhibitor or/and cPAP (c-Phosphorylation Inhibitor) for preventing or treating prostatic cancer or castration-resistant prostatic cancer, wherein the tyrosine phosphorylation inhibitor comprises at least one of Y < 279 >, Y < 357 > and Y < 488 >, and the tyrosine phosphorylation inhibitor can be used for preventing or treating prostatic cancer or castration-resistant prostatic cancer. According to the invention, Se-coated SiO2 and docetaxel are combined for use, so that not only can the direct anticancer effect of selenium in Se-coated SiO2 be played, but also the killing effect of the chemotherapeutic drug docetaxel on cancer cells can be improved, and the application has important clinical significance. 本发明属于抗肿瘤技术领域，