Detection kit for systemic lupus erythematosus

• Main Authors: HU XIAOMING, MAO HUIFENG, GUO LEILEI, ZHAO FENG, ZHANG CHUNJIE, CHEN TONGGE
• Format: Patent
• Language: Chinese; English
• Published: 31.05.2024
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention discloses a detection kit for systemic lupus erythematosus. The detection kit comprises a first reagent and a second reagent, the first reagent comprises a biotin-labeled IP-10 coated antibody which is connected with streptavidin magnetic particles; and the second reagent comprises an IP-10 labeled antibody labeled by azacridine ester. The kit for judging the systemic lupus erythematosus by using the content of the IP-10 is prepared for the first time, the kit is used for screening antibodies and antigens and optimizing components and proportions of other related reagents, and the detection kit for detecting the IP-10 by using a magnetic particle chemiluminescence technology is obtained. According to the method, a biotin-IP-10 coated antibody connected with streptavidin magnetic particles, an IP-10 labeled antibody labeled by acridinium ester and IP-10 in a sample are combined to form a sandwich compound for detection. The kit for detecting the IP-10 has the characteristics of simplicity, conven