Screening method of indication virus for irradiation disinfection

• Main Authors: DANG XUHONG, LIU HONGYAN, DONG JUANCONG, LIU XIAOMING, REN YUE, HARA MASAYOSHI, CHENG JIAO, WANG CHAO
• Format: Patent
• Language: Chinese; English
• Published: 31.05.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROCESSES USING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention relates to a screening method of indication viruses for irradiation disinfection, which comprises the following steps: screening a series of viruses without DNA (Deoxyribose Nucleic Acid) envelopes as samples by taking the sizes and envelop capsids of the viruses as selection indexes; performing irradiation treatment of different doses on the virus sample to obtain virus titers of different viruses subjected to irradiation treatment and virus titers of untreated viruses, comparing the differences between the virus titers and the virus titers, and screening virus inactivation titers gt under the same dose; the virus with the 4Log10 value is used as an indication virus sensitive to irradiation sterilization. The screened indication virus can be used for quantitatively evaluating the removal/inactivation effectiveness of the DNA envelope-free virus in the actual production process, and can be used as a biological irradiation indicator in the cold-chain food irradiation process. 本发明涉及一种用于辐照消杀的指示病毒的筛