Synthetic method for continuously preparing ethyl acetoacetate by using immobilized catalyst

• Main Authors: GONG HONGXIANG, SUN ZENGMIN, SUN YANAN, ZHAO PANFENG, WANG LAN, LOU LILI
• Format: Patent
• Language: Chinese; English
• Published: 31.05.2024
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention relates to the technical field of chemical engineering, and discloses a synthetic method for continuously preparing ethyl acetoacetate by using an immobilized catalyst, which comprises the following operation steps: immobilizing alkaline anion resin to a curing bed; controlling the temperature of a curing bed, and reacting diketene and absolute ethyl alcohol according to a molar ratio in the curing bed to obtain an ethyl acetoacetate crude product; rectifying and purifying the ethyl acetoacetate crude product to obtain qualified ethyl acetoacetate; the alkaline anion resin in the curing bed is activated after a certain amount of ethyl acetoacetate is prepared, and is continuously used after being activated. The operation method is simple, safe and reliable, the reaction efficiency is high, and the product quality is good; the alkaline anion resin catalyst can be activated and regenerated after catalytic inactivation, recycling is achieved, the production cost is effectively reduced, environmenta