Photoreceptor cells for retina and macular repair

• Main Authors: ELDRED KAREN, SINGH MANMOHAN, HSIEH KEVIN, JOHNSTON ROBERT, HARDNIK STEFAN, MCNERNEY CHRISTOPHER
• Format: Patent
• Language: Chinese; English
• Published: 24.05.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The degenerative macular disease is a main cause of uncurable blindness. The present disclosure relates to cell-based therapeutic agents for retinal and macular repair comprising defined retinal cell subtypes, including short (S)-wavelength, medium (M)-wavelength, and long (L) wavelength sensitive cone cell photoreceptors, methods of making such cell-based therapeutic agents, and methods of using such therapeutic agents. 退行性黄斑疾病是不可治愈的失明的主要原因。本公开涉及用于视网膜和黄斑修复的基于细胞的治疗剂，其包含定义的视网膜细胞亚型，包括短(S)-波长、中(M)-波长和长(L)波长敏感的视锥细胞光感受器，本公开还涉及制造这类基于细胞的治疗剂的方法以及使用这类治疗剂的方法。