Method for efficiently synthesizing nitrogen-containing organic matter from P-S double-ylide derivative

• Main Author: YANG XIAOYONG
• Format: Patent
• Language: Chinese; English
• Published: 24.05.2024
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention relates to a method for efficiently synthesizing a nitrogen-containing organic matter from a P-S double-ylide derivative, which comprises the following steps: reacting the P-S double (ylide) derivative with a transition metal complex MLn at normal temperature to form a stable adduct, then separating the adduct from a reaction system, and removing thioether groups from the adduct in the presence of a cocatalyst SbF5 to form a carbene intermediate; and reacting the carbene intermediate with N2 to generate the nitrogen-containing organic compound. The adduct is separated from a reaction system, CO in the system can be completely removed, and the problems that in an original technical route, due to the fact that CO and carbene are subjected to side reaction, separation and purification of a target product are difficult, and the production cost is increased are solved. The cocatalyst SbF5 is introduced for subsequent reaction, so that the reaction energy barrier during removal of thioether groups can