Application of hypericin to preparation of medicine for treating chronic pulmonary obstruction

• Main Authors: YE ZAITING, YIN ZHANGYONG, CAO ZHUO, CAI XIAOPING, PAN JIONGWEI, XU CUNLAI
• Format: Patent
• Language: Chinese; English
• Published: 24.05.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses application of hypericin to preparation of a medicine for treating chronic pulmonary obstruction. The hyperforin is added, so that the viability of II-type alveolar cells of mice can be improved, cell proliferation is promoted, inflammatory response and cell apoptosis are reduced, DNA damage is relieved, oxidative stress response is reduced, and the effect of relieving chronic pulmonary obstruction is achieved. The invention provides new scientific research evidence for research and development of drugs for relieving chronic pulmonary obstruction, and has important clinical application value and development value. 本发明公开了加贯叶金丝桃素在制备治疗慢性肺阻塞药物中的应用。加贯叶金丝桃素能够提高小鼠II型肺泡细胞活率，促进细胞增殖，减少炎症反应和细胞凋亡，减轻DNA损伤，降低氧化应激反应，具有减轻慢性肺阻塞的作用。本发明为研发缓解慢性肺阻塞药物提供了新的科研证据，具有重要的临床应用价值和开发价值。