Method for regulating kinase activity and application thereof

The invention provides a method for regulating kinase activity and application thereof. Specifically, the invention provides an application of an active component for targeted regulation of metabolite expression quantity, the active component is used for preparing a pharmaceutical composition, and t...

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Bibliographic Details
Main Authors WANG KAIHUA, DING CHUNYONG, GAO DAMING, ZHANG AO
Format Patent
LanguageChinese
English
Published 17.05.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides a method for regulating kinase activity and application thereof. Specifically, the invention provides an application of an active component for targeted regulation of metabolite expression quantity, the active component is used for preparing a pharmaceutical composition, and the pharmaceutical composition is used for preventing and/or treating AMPK kinase mediated metabolism-related diseases. And the metabolite is selected from the group consisting of 3-phosphoglyceric acid, 2-phosphoglyceric acid, pyruvic acid, or a combination thereof. 本发明提供了一种调节激酶活性的方法及其用途。具体地，本发明提供了一种靶向调控代谢物表达量的活性成分的用途，所述活性成分用于制备药物组合物，所述药物组合物用于预防和/或治疗AMPK激酶介导的代谢相关疾病；且所述的代谢物选自下组：3-磷酸甘油酸、2-磷酸甘油酸、丙酮酸，或其组合。
Bibliography:Application Number: CN202211436260