Detection of bioactive agents in surrounding media

• Main Author: STEINER SANDRA
• Format: Patent
• Language: Chinese; English
• Published: 14.05.2024
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

A sensor chip is presented that is operably coupled to a sensing device to detect one or more bioactive agents in a surrounding medium. The sensor chip comprises: a reaction tank, wherein the reaction tank contains a plurality of receptor protein complexes; and a membrane separating the reaction cell from the surrounding medium and being permeable to the one or more bioactive agents wherein the receptor protein complex is configured to bind to the one or more bioactive agents in the reaction cell, such that a detectable state change of at least a portion of the receptor protein complex is induced. 提出了一种传感器芯片，所述传感器芯片可操作地耦合到感测装置以检测周围介质中的一种或多种生物活性剂。所述传感器芯片包括：反应池，所述反应池含有多种受体蛋白复合物；和膜，所述膜将所述反应池与所述周围介质分开并且对所述一种或多种生物活性剂是可透过的，其中所述受体蛋白复合物被配置成与所述反应池中的一种或多种生物活性剂结合，使得诱导所述受体蛋白复合物的至少一部分的可检测的状态变化。