Pre-filled microneedle injector for injection of biomacromolecular pharmaceutical preparation

• Main Authors: GU ZHEN, MAO JUNSONG, LIU XIAOXI, LIU WEIWEI, GUO ZHIFENG, TIAN YUANRUI, WANG LUFAN
• Format: Patent
• Language: Chinese; English
• Published: 14.05.2024
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS

The pre-filled microneedle injector comprises a needle cylinder, a piston and a needle head, the needle cylinder is of a hollow structure, a limiting ring is arranged at the open end of the needle cylinder, the piston extends into the needle cylinder from one side of the limiting ring and can move up and down in the needle cylinder, a rubber ring is arranged at the bottom end of the piston, and a pushing handle is arranged at the top of the piston; the needle head is fixed to the side, away from the limiting ring, of the needle cylinder and comprises a connecting part and needle tubes, the connecting part extends out of the needle cylinder, and at least one needle tube is embedded into the connecting part in an in-line mode. The syringe is used for injection of biological macromolecular medicine preparations and complex preparations, especially mRNA vaccines or medicine preparations needing to be pre-injected in a micro-injection mode, the hydrophilic film on the inner wall of the syringe enables biological m