Application of P3H2 in preparation of medicine for treating chronic obstructive pulmonary disease

• Main Authors: YE ZAITING, YIN ZHANGYONG, CAO ZHUO, CAI XIAOPING, PAN JIONGWEI, XU CUNLAI
• Format: Patent
• Language: Chinese; English
• Published: 14.05.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to the technical field of biological medicine, in particular to application of P3H2 in preparation of medicine for treating chronic obstructive pulmonary disease, the P3H2 gene can enhance alveolar epithelial cell activity and new tube forming ability and inhibit apoptosis, the invention further expands a new medical application of the P3H2 gene, and the P3H2 gene can be applied to preparation of medicine for treating chronic obstructive pulmonary disease. The invention also provides a P3H2 gene as a treatment target and a treatment mode of chronic obstructive pulmonary disease (COPD). 本发明涉及生物医药技术领域，尤其涉及P3H2在制备治疗慢性阻塞性肺疾病药物中的应用，本发明的P3H2基因可以增强肺泡上皮细胞活性和新管形成能力、抑制凋亡，本发明还拓展了P3H2基因的一种新的医药用途，本发明还提供的P3H2基因作为慢性阻塞性肺疾病（COPD）治疗靶点及治疗方式。