Preparation method of antioxidant Mo2C-TA nanosheet and application of antioxidant Mo2C-TA nanosheet in diabetes wound healing and pulmonary fibrosis treatment

• Main Authors: LI CAIXIA, YANG QI, REN YAPING, JIA HUIMIN, HE WEIWEI, SI JINGJING
• Format: Patent
• Language: Chinese; English
• Published: 03.05.2024
• Subjects: CHEMISTRY; COMPOUNDS THEREOF; HUMAN NECESSITIES; HYGIENE; INORGANIC CHEMISTRY; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NANOTECHNOLOGY; NON-METALLIC ELEMENTS; PERFORMING OPERATIONS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; TRANSPORTING

The invention discloses a preparation method of an antioxidant Mo2C-TA nanosheet and application of the antioxidant Mo2C-TA nanosheet in diabetes wound healing and pulmonary fibrosis treatment, and belongs to the technical field of nano materials. The preparation method comprises the following steps: (1) carrying out hydrochloric acid/lithium fluoride high-temperature hydrothermal treatment on MAX-phase Mo2Ga2C powder to etch a Ga layer, and carrying out centrifugal washing and drying to obtain multiple layers of Mo2C; (2) carrying out intercalation treatment on the multi-layer powder by virtue of an intercalator tetramethylammonium hydroxide and an anti-oxidation ascorbic acid agent under a high-temperature condition, carrying out centrifugal washing, and carrying out ultrasonic stripping treatment, so as to obtain a thin layer Mo2C; and (3) selecting tannic acid (TA) as an antioxidant, and carrying out electrostatic adsorption to obtain the thin-layer Mo2C-TA nanosheet with a stable physiological environmen