Application of taurine in preparation of medicine for preventing and treating animal fatty liver

• Main Authors: SAN JISHUANG, YANG JIANCHENG, OUYANG GUANGYI, WU GAOFENG, LI WEIWEI
• Format: Patent
• Language: Chinese; English
• Published: 03.05.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the field of medicines, and discloses application of taurine in preparation of a medicine for preventing and treating animal fatty liver. According to the application of the taurine in the aspect of improving the animal fatty liver, cell tests and animal feeding tests prove that the taurine can relieve fatty degeneration of human hepatocyte lines caused by mixed long-chain fatty acids; liver injury and liver fatty degeneration of mice fed with high-fat diet and laying hens fed with high-energy low-protein feed can be improved, animal fatty liver can be prevented and treated, and the feed has important significance on animal production. 本发明属于医药领域，公开了牛磺酸在制备用于防治动物脂肪肝的药物中的应用。本发明发现牛磺酸在改善动物脂肪肝方面的用途，通过细胞试验和动物饲养试验均证明，牛磺酸不仅可以缓解混合长链脂肪酸导致的人肝细胞系脂肪变性，还可以改善高脂饮食饲喂的小鼠和高能低蛋白饲料饲喂的蛋鸡肝脏损伤及肝脏脂肪变性，能够防治动物脂肪肝的发生，对动物生产具有重要意义。