Detection of chemicals in sweat of subject

• Main Authors: BEDIOUI, FATHI, CHEN YONG, GRIVEAU SOPHIE, AMATORE CRISTIAN, SERRA KATHERINE, FOUVEL GILLES, TOIN, LAURENT
• Format: Patent
• Language: Chinese; English
• Published: 26.04.2024
• Subjects: DIAGNOSIS; HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; MEDICAL OR VETERINARY SCIENCE; PHYSICS; SURGERY

The invention relates to a detection device for placement in a survey area of the epidermis of a human or animal subject in order to detect at least nitric oxide dissolved in sweat, said device comprising: a structure (1) defining a microfluidic passage for guiding the flow of sweat, said structure comprising an inlet aperture (4) allowing the passage of sweat from the epidermis, the microfluidic pathway comprises at least one microfluidic channel (9) communicating with the inlet aperture, at least one electrochemical sensor (10) comprising at least four electrodes arranged in series in the longitudinal direction of the microfluidic channel, the at least four electrodes comprising a reference electrode, at least two working electrodes and a counter electrode, the electrochemical sensor is configured to generate a signal indicative of the concentration of nitric oxide and further perform depletion and/or to generate a signal indicative of the flow rate of the sweat flow. 本发明涉及一种用于放置在人或动物受试者的表皮的调查区以便至少检测溶于汗液中的一