Ratio-dependent fluorescent nanoprobe for detecting ciprofloxacin as well as preparation method and application of ratio-dependent fluorescent nanoprobe

• Main Authors: HAO YUANQIANG, WENG PEI, ZHOU ZAICHUN, TANG ZILONG, CHEN SHU, LIU QIUHUA
• Format: Patent
• Language: Chinese; English
• Published: 26.04.2024
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; ADHESIVES; CHEMISTRY; DYES; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE; MEASURING; METALLURGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; NATURAL RESINS; ORGANIC CHEMISTRY; PAINTS; PHYSICS; POLISHES; TESTING

The invention discloses a ratio type fluorescent nanoprobe for detecting ciprofloxacin as well as a preparation method and application of the ratio type fluorescent nanoprobe, and belongs to the technical field of fluorescent materials. The probe is obtained by mixing 2-aminoterephthalic acid, adenine ribonucleotide and a rare earth terbium salt solution, stirring at room temperature, carrying out sufficient reaction, centrifuging, collecting precipitate and drying. The probe shows blue fluorescence, and the maximum emission wavelength is 426 nm; after the ciprofloxacin is added, due to the coordination and fluorescence sensitization characteristics of the ciprofloxacin, the green fluorescence of the rare earth element is obviously enhanced, and the maximum emission wavelength is 544 nm, so that the high-sensitivity ratio type detection of the ciprofloxacin can be realized. The nano probe has the advantages of high selectivity and high sensitivity on ciprofloxacin, the response speed is high, the response lin