Multispecific antigen binding proteins

• Main Authors: LU XIAOFENG, CHENG YONGQING, GU JIJIE, WANG ZHUOZHI, FAN XINZHAO, XU JIANQING, CHEN YUNYING
• Format: Patent
• Language: Chinese; English
• Published: 19.04.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present disclosure provides multispecific and multivalent antigen binding proteins. In one aspect, the disclosure provides a multispecific antigen binding protein comprising a first antigen binding site comprising a first VHH that specifically binds to a first epitope; and a second antigen binding site specifically binding to the second epitope. 本公开提供了多特异性和多价的抗原结合蛋白。一方面，本公开提供了一种多特异性抗原结合蛋白，其包括第一抗原结合位点，该第一抗原结合位点包含与第一表位特异性结合的第一VHH；以及与第二表位特异性结合的第二抗原结合位点。