Lactobacillus fermentum GLF-217 and application thereof in ulcerative colitis and hyperlipemia and reduction of organ injury

• Main Authors: WANG ZIYUAN, YU LANXIU, CHEN YUNHUI, LIU AIJIE, BAI DALIN
• Format: Patent
• Language: Chinese; English
• Published: 12.04.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DAIRY PRODUCTS, e.g. MILK, BUTTER, CHEESE; ENZYMOLOGY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MAKING THEREOF; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MILK OR CHEESE SUBSTITUTES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The invention discloses a strain of Lactobacillus fermentum GLF-217, and a preparation method of the Lactobacillus fermentum GLF-217. The lactobacillus fermentum GLF-217 is preserved in the China General Microbiological Culture Collection Center on September 4, 2023, and the preservation number of the lactobacillus fermentum GLF-217 is CGMCC No. 28336. The lactobacillus fermentum GLF-217 provided by the invention can simultaneously and effectively treat ulcerative colitis and hyperlipidemia and reduce organ injury, and a technical scheme is provided for combined treatment of ulcerative colitis, hyperlipidemia and organ injury. 本发明公开了一株发酵乳杆菌(Lactobacillus fermentum)GLF-217。所述发酵乳杆菌GLF-217于2023年9月4日保存于中国微生物菌种保藏管理委员会普通微生物中心，保藏号为CGMCC No.28336。本发明提供的发酵乳杆菌GLF-217，能够同时有效治疗溃疡性结肠炎、高脂血症和降低器官损伤，为溃疡性结肠炎、高脂血症和器官损伤三者的联合治疗提供了技术方案。