Oocyte activation solution, oocyte activation combined solution and application thereof

• Main Authors: LI XINGYAN, YANG YUN, WANG ZHISONG, LI PEISHANG
• Format: Patent
• Language: Chinese; English
• Published: 09.04.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention belongs to the technical field of assisted reproduction, and particularly relates to an oocyte activation solution, an oocyte activation combined solution and application thereof. The oocyte activation liquid can activate oocytes in an atmospheric environment, increase Ca < 2 + > influx and activate Ca < 2 + > oscillation, so that the activation defects of the oocytes are reduced, and the fertilization rate is increased. On the basis, the oocyte activation solution (oocyte activation solution A) and the oocyte activation solution B form an oocyte activation combined solution, so that the oocytes can be further activated, the oxidative stress reaction is reduced, and the blastocyst rate is increased. The oocyte activation solution A and the oocyte activation solution B are combined for use, so that a synergistic interaction effect can be achieved, oocytes are effectively activated, and the fertilization rate and the blastocyst development rate are remarkably increased. 本发明属于辅助生殖技术领域，具体涉及一种卵母细胞激活液