Endophytic fungus broom cladosporium F5 and application thereof

• Main Authors: PIAO MEIZI, CHEN TIEJUN, CHU GUANGPENG, MEN YANFANG, WANG FENGWU
• Format: Patent
• Language: Chinese; English
• Published: 05.04.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The invention discloses an endophytic fungus broom cladosporium F5 and application thereof. The cladosporium cladosporium F5 is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.40884. The nucleotide sequence of ITS of the cladosporium cladosporium F5 is as shown in SEQ ID No.1, and the nucleotide sequence of Bt of the cladosporium cladosporium F5 is as shown in SEQ ID No.2. The cladosporium cladosporium F5 has the effect of inhibiting aggregation of acetylcholin esterase and A beta protein, has a good inhibition effect, also has strong capability of producing cellulase, pectinase and protease, can be used for fermentation production of the three biological enzymes, and is simple to operate. The acetylcholin esterase and the A beta protein are factors related to the Alzheimer's disease, so that the broom cladosporium F5 can play a positive role in treating the Alzheimer's disease. 本发明公开了一株内生真菌帚枝霉F5及其应用。所述帚枝霉F5保藏于中国微生物菌种保藏管理委员会普通微生物中心，保藏编号