Novel sodium alginate antibacterial hydrogel material as well as preparation method and application thereof
The invention relates to the technical field of biological medicines, and discloses a novel sodium alginate antibacterial hydrogel material as well as a preparation method and application thereof. The preparation method comprises the following steps: 1, adding a catalyst into a sodium alginate solut...
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Main Authors | , , |
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Format | Patent |
Language | Chinese English |
Published |
02.04.2024
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Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to the technical field of biological medicines, and discloses a novel sodium alginate antibacterial hydrogel material as well as a preparation method and application thereof. The preparation method comprises the following steps: 1, adding a catalyst into a sodium alginate solution, mixing, adding dopamine, reacting, and purifying and drying a product to obtain SA-DA; step 2, dissolving SA-DA, adding dopamine, and carrying out polymerization reaction under an alkaline condition to obtain an SA-DA (at) PDA precursor solution; and step 3, adding a CaCO3 suspension and D-(+) gluconic acid delta-lactone into the SA-DA (at) PDA precursor solution, mixing, and curing to obtain the novel alginic acid antibacterial hydrogel material. According to the invention, sodium alginate is used as a base material, a multi-crosslinked hydrogel material is obtained through dopamine grafting, dopamine self-polymerization and calcium carbonate crosslinking, and the material not only has excellent biocompatibil |
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Bibliography: | Application Number: CN202311610988 |