Veterinary oral nano liquid preparation taking macrolide medicine as active ingredient

• Main Authors: ZHAN SHENSHAN, LI XINGYE, WANG YAN
• Format: Patent
• Language: Chinese; English
• Published: 02.04.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the technical field of medicines, and provides a veterinary oral nano liquid preparation taking macrolide medicines as active ingredients. The liquid preparation disclosed by the invention consists of macrolide drugs, a wetting agent, a solubilizer, a carrier, a clarifying agent triethyl citrate, a flavoring agent, a flavoring agent, a pH regulator and water. Through the same synergistic effect of the wetting agent, the solubilizer and the carrier, dispersion and dissolution of the indissolvable macrolide medicine in water are promoted; the clarifying agent promotes clarity of the liquid formulation; the flavoring agent and the flavoring agent synergistically improve the palatability of the liquid preparation; and the pH regulator maintains the stability of the macrolide medicine. The liquid preparation provided by the invention overcomes the difficulties of low clarity, low solubility, instability, fast degradation and poor palatability of macrolide drugs in an aqueous solution, ensu