Silver complex fluoride {bis (1, 3, 5-triaza-7-phosphaadamantane) silver fluoride}-novel therapeutic agents for dental caries management

• Main Authors: ZHU ZHENXIONG, LONG YINGQI
• Format: Patent
• Language: Chinese; English
• Published: 29.03.2024
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The agent for preventing dental caries is a silver complex fluoride (SCF) of the following structure: [Ag (1, 3, 5-triaza-7-phosphaadamantane) 2] F (Ag (PTA) 2F). The medicament effectively prevents dental caries and promotes remineralization of caries lesions. The agent results in a maximum reduction in tooth staining and tissue inflammation. The therapeutic agent may be selectively applied to dental caries or other sites of damaged tissue in the oral cavity. 用于阻止牙科龋齿的药剂是以下结构的银络合氟化物(SCF)：[Ag(1,3,5-三氮杂-7-磷金刚烷)2]F，(Ag(PTA)2F)。该药剂有效地阻止了牙科龋齿并促进龋病变的再矿化。该药剂导致最大限度地减少牙齿染色和组织炎症。治疗剂可以选择性地应用于口腔中的龋齿或其他受损组织的部位。