Preparation method of 2-hydroxy-benzonitrile

• Main Authors: JIANG SHIFENG, WANG XICHENG, ZHANG SHAOCHUN, LIU XIAORAN, MOU XINDONG
• Format: Patent
• Language: Chinese; English
• Published: 29.03.2024
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a preparation method of 2-hydroxy-benzonitrile, which comprises the following steps: introducing a solid, molten or solution-state raw material salicylamide into a continuous reactor along with carrier gas and carbon dioxide, filling the continuous reactor with a solid acid-base catalyst, and carrying out one-step reaction on the salicylamide in the presence of the carbon dioxide to prepare the 2-hydroxy-benzonitrile. The method can effectively improve the selectivity of 2-hydroxy-benzonitril, reduce the emission of three wastes in the preparation of 2-hydroxy-benzonitril by the existing process, improve the product quality, reduce the production cost, improve the production safety, reduce the generation amount of phenol and improve the product quality. 本发明公开了一种水杨腈的制备方法，该方法将固体、熔融状态或溶液状态的原料水杨酰胺随载气与二氧化碳通入连续式反应器中，所述连续式反应器中填充有固体酸碱催化剂，使水杨酰胺在二氧化碳的存在下一步反应制备水杨腈。通过此方法可以有效提高水杨腈的选择性，减少通过现有工艺制备水杨腈存在三废排放量，提高产品质量，降低生产成本，提高生产安全性，减少苯酚的生成量，提高产品质量。