Compound with kinase inhibition function as well as preparation and application thereof

The invention discloses an HPK1 kinase inhibitor as well as a preparation method and application thereof. Specifically, the invention relates to a compound shown as a formula (I), and the compound has HPK1 inhibitory activity and is used for preparing a pharmaceutical composition for treating cancer...

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Main Authors LIU SHENGYANG, SHI QIAN, NIE SHICHANG, WANG BING, ZHANG JIANHUA, XU YUAN, SHOU JIANYONG, CHENG ZHANLING, ZHAO HAIXIA, ZHANG YI, FENG ZHIYONG, XU LINGLING, JIANG LEI, KIM HYUN
Format Patent
LanguageChinese
English
Published 22.03.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention discloses an HPK1 kinase inhibitor as well as a preparation method and application thereof. Specifically, the invention relates to a compound shown as a formula (I), and the compound has HPK1 inhibitory activity and is used for preparing a pharmaceutical composition for treating cancers and other diseases related to HPK1 activity. # imgabs0 # 一种HPK1激酶抑制剂及其制备方法和应用。具体地，一种如式(I)所示的化合物，所述的化合物具有HPK1抑制活性，用于制备治疗癌症和其他HPK1活性相关疾病的药物组合物。#imgabs0#
Bibliography:Application Number: CN202280029140