PROCESS FOR THE PREPARATION OF ACETAPRAL DIOascorbate SALTS AND THE USE THEREOF FOR THE TREATMENT OF INFUNCTIVE FUNGAL INFECTIONS RESISTANT TO CONDITIONAL

• Main Authors: FERRARI, VALERIO, M, M.VIGILANT, BRUZZESE TEODOR, BAGGIO MARIA CRISTINA, KALIZI ALIREZA, GRISENTI, PAOLO
• Format: Patent
• Language: Chinese; English
• Published: 19.03.2024
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SUGARS

The present invention relates to a process for the preparation of acipatran diascorbate and its use for improving the treatment of aggressive fungal infections that are evidenced/prevailing resistance to traditional antifungal agents. 本发明涉及制备阿昔帕曲星二抗坏血酸盐的方法及其用于改善治疗侵袭性真菌感染中的用途，所述侵袭性真菌感染有证据证明/普遍存在对传统抗真菌剂的抗性。