Iron (III) macrocyclic complexes with mixed hydroxyl pendant groups as MRI contrast agents
The present application describes novel Fe (III) macrocyclic complexes having a hydroxyl pendant group bearing a third anionic helper group for improving in vivo MR imaging. The complex has the following general structure: # imgabs0 #, wherein high-spin Fe (III) is chelated with the complex. Also de...
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Main Authors | , , , , |
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Format | Patent |
Language | Chinese English |
Published |
19.03.2024
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Subjects | |
Online Access | Get full text |
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Summary: | The present application describes novel Fe (III) macrocyclic complexes having a hydroxyl pendant group bearing a third anionic helper group for improving in vivo MR imaging. The complex has the following general structure: # imgabs0 #, wherein high-spin Fe (III) is chelated with the complex. Also described herein are novel Fe (III) macrocyclic complexes having a hydroxypropyl pendant group bearing a third anionic helper group for improving in vivo MR imaging. Said complexes have the following general structure: # imgabs 1 #
本申请描述新型Fe(III)大环配合物,其具有带有第三阴离子辅助基团的羟基侧基,用于改善体内MR成像。所述配合物具有以下一般结构:#imgabs0#其中高自旋Fe(III)与其螯合。本申请还描述新型Fe(III)大环配合物,其具有带有第三阴离子辅助基团的羟丙基侧基,用于改善体内MR成像。所述配合物具有以下一般结构:#imgabs1# |
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Bibliography: | Application Number: CN202280035671 |