Preparation method of 1, 3-propanedisulfonyl fluoride

• Main Authors: CHANG YONGTAO, KONG FANXIAO, MIAO QIANGQIANG, ZHEN HUANZHEN, GUO PENGCHONG
• Format: Patent
• Language: Chinese; English
• Published: 19.03.2024
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a preparation method of 1, 3-propanedisulfonyl fluoride, 1, 3-dibromopropane and sodium sulfite are used as starting materials, the 1, 3-propanedisulfonyl fluoride is prepared through a three-step method, in the first step of reaction, the 1, 3-dibromopropane and the sodium sulfite are used as reaction materials, water is used as a solvent, and 1, 3-sodium propanedisulfonate is prepared through heating; in the second step of reaction, 1, 3-sodium propanedisulfonate and thionyl chloride are used as reaction materials to prepare 1, 3-propanedisulfonyl chloride; 3, preparing 1, 3-propanedisulfonyl fluoride by taking sodium 1, 3-propanedisulfonate and potassium fluoride as reaction materials and acetonitrile as a solvent; the reaction conditions are mild, the used solvent and other materials are common industrial production raw materials, raw materials with high toxicity are not involved, the process cost is low, and the method is suitable for industrial mass production; the prepared produ