Peptide tag and nucleic acid encoding same

The present invention provides a peptide tag and a nucleic acid encoding the same. The peptide tag of the present invention can reduce aggregation of proteins in cells. Specifically disclosed is a peptide tag in which 5% or more but less than 45% of the amino acids constituting the amino acid sequen...

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Bibliographic Details
Main Author KABAYAMA HIROYUKI
Format Patent
LanguageChinese
English
Published 15.03.2024
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Summary:The present invention provides a peptide tag and a nucleic acid encoding the same. The peptide tag of the present invention can reduce aggregation of proteins in cells. Specifically disclosed is a peptide tag in which 5% or more but less than 45% of the amino acids constituting the amino acid sequence are acidic amino acids and 20% or more of (b) the amino acids constituting the amino acid sequence are amino acids selected from the group consisting of F, P, Y, G, S, Q, N, and A. 本发明提供肽标签和编码该肽标签的核酸。本发明的肽标签可以降低细胞内的蛋白质的聚集性。本发明的肽标签具体而言可以为构成氨基酸序列的氨基酸的5%以上且小于45%为酸性氨基酸且(b)构成氨基酸序列的氨基酸的20%以上为选自由F、P、Y、G、S、Q、N和A组成的组中的氨基酸的肽标签。
Bibliography:Application Number: CN202280052448