Process for making oil-in-water emulsions with low PFAT5 value in mixture for parenteral nutrition

• Main Authors: QUINCHIA BUSTAMENTE LIDA A, GALLEGOS-MONTES CRISPULO, TURCANU, MIHAELA, BRITO DE LA FUENTE EDMUNDO, SIEGERT, NADJA, VERDEBAEZGHI, GUTACIU
• Format: Patent
• Language: Chinese; English
• Published: 15.03.2024
• Subjects: EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKINGOILS; FOODS OR FOODSTUFFS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a process for the manufacture of an oil-in-water emulsion which, after mixing said emulsion with a solution of amino acids and glucose suitable for parenteral administration, maintains a PFAT5 value below 0.05% for at least 24 hours, preferably at least 48 hours. 本发明涉及一种用于制造水包油乳液的方法，在将所述乳液与适于肠胃外施用的氨基酸和葡萄糖溶液混合之后，所述乳液的PFAT5值保持低于0.05％持续至少24小时，优选至少48小时。