Method for measuring protein C and activated protein C
The present invention relates to a method of measuring the level of Protein C (PROC), preferably Activated Protein C (APC), in a subject in need thereof, comprising: a step of enzymatic digestion of one or more biological samples isolated from the subject; and a step of measuring the level of the pe...
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Format | Patent |
Language | Chinese English |
Published |
08.03.2024
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Abstract | The present invention relates to a method of measuring the level of Protein C (PROC), preferably Activated Protein C (APC), in a subject in need thereof, comprising: a step of enzymatic digestion of one or more biological samples isolated from the subject; and a step of measuring the level of the peptide of SEQ ID NO: 1 (LGEYDLR and/or of the peptide of SEQ ID NO: 2 (TFVLNFIK), wherein the level of SEQ ID NO: 1 and/or of SEQ ID NO: 2 corresponds to the level of PROC, preferably APC, present in said one or more biological samples. Methods of classifying and prognosing a therapeutic response in a subject are also included.
本发明涉及一种测量有需要的对象中蛋白C(PROC)、优选活化蛋白C(APC)水平的方法,该方法包括:对从对象分离的一个或多个生物样本进行酶促消化的步骤;和测量SEQ ID NO:1(LGEYDLR)的肽和/或SEQ ID NO:2(TFVLNFIK)的肽的水平的步骤,其中SEQ ID NO:1和/或SEQ ID NO:2的水平对应于所述一个或多个生物样本中存在的PROC、优选APC的水平。还包括对对象进行分类和预后治疗反应的方法。 |
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AbstractList | The present invention relates to a method of measuring the level of Protein C (PROC), preferably Activated Protein C (APC), in a subject in need thereof, comprising: a step of enzymatic digestion of one or more biological samples isolated from the subject; and a step of measuring the level of the peptide of SEQ ID NO: 1 (LGEYDLR and/or of the peptide of SEQ ID NO: 2 (TFVLNFIK), wherein the level of SEQ ID NO: 1 and/or of SEQ ID NO: 2 corresponds to the level of PROC, preferably APC, present in said one or more biological samples. Methods of classifying and prognosing a therapeutic response in a subject are also included.
本发明涉及一种测量有需要的对象中蛋白C(PROC)、优选活化蛋白C(APC)水平的方法,该方法包括:对从对象分离的一个或多个生物样本进行酶促消化的步骤;和测量SEQ ID NO:1(LGEYDLR)的肽和/或SEQ ID NO:2(TFVLNFIK)的肽的水平的步骤,其中SEQ ID NO:1和/或SEQ ID NO:2的水平对应于所述一个或多个生物样本中存在的PROC、优选APC的水平。还包括对对象进行分类和预后治疗反应的方法。 |
Author | MENA MORA SALVADOR PALLARDO CALATAYUD FEDERICO VICENTE CARBONELL MONLEON NEVES GARCIA GIMENEZ JOSE LUIS |
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DocumentTitleAlternate | 蛋白C和活化蛋白C的测量方法 |
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Title | Method for measuring protein C and activated protein C |
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