Engineered and fully-functionally tailored glycoproteins

• Main Authors: FORADOR, RAINER, FARID MOYAYE AMIREZA, MALLY MANUELA
• Format: Patent
• Language: Chinese; English
• Published: 02.02.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROCESSES USING MICROORGANISMS; SPIRITS; VINEGAR; WINE

This document relates to engineered and fully-functionally tailored glycoproteins. Described herein are compositions and methods for producing glycosylated proteins in vitro and in vivo. The methods include using a host cell to produce a glycosylated protein. Glycosylated proteins produced using these methods and uses thereof are also described herein. 本文涉及工程化且完全-功能定制的糖蛋白。本文描述了体外和体内产生糖基化蛋白的组合物和方法。所述方法包括使用宿主细胞来产生糖基化蛋白。本文还描述了使用这些方法产生的糖基化蛋白及其用途。