RNAi nanoparticles and methods of use thereof in agriculture

• Main Authors: SADOT MUZKA NADJA, PESKY, ZBIGNIEW, L, SHOSEYOV, ODED, AVITAL AMIT, SCHROEDER AVI
• Format: Patent
• Language: Chinese; English
• Published: 30.01.2024
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

The present invention provides a nanoparticle comprising: (a) an amphiphilic copolymer comprising an ionizable polymer covalently bound to a hydrophobic domain; and a polynucleotide comprising from 60 to 500 nucleobases. Compositions comprising the nanoparticles of the invention and methods of using...