Preparation and application of deuterated 4-phenylpiperidine-4-alcohol compound

• Main Authors: WU JIUMEI, CAO ZHENGHONG, FAN MEIMEI
• Format: Patent
• Language: Chinese; English
• Published: 26.01.2024
• Subjects: APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to preparation and application of a deuterated 4-phenylpiperidine-4-alcohol compound, the structural general formula of the compound is as shown in formula (I) or formula (II), and also discloses preparation and application of the compound as well as pharmaceutically acceptable salts and pharmaceutical compositions containing the compound. The compounds of the present invention are useful in the treatment of pain. 本发明涉及氘代的4-苯基哌啶-4-醇类化合物的制备及其用途，该化合物的结构通式为式（I）或者式（II），同时还公开了该化合物的制备及其用途以及含有该化合物的药学上可接受的盐、药物组合物。本发明的化合物可用于疼痛的治疗。