Hyperimmune egg product for treating or preventing alcoholic liver disease and graft versus host disease

• Main Authors: IYER, SRIDHAR, V, PATEL SHRENIK
• Format: Patent
• Language: Chinese; English
• Published: 23.01.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

In one aspect, the disclosure relates to a method of preventing or treating alcoholic liver disease or graft versus host disease in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a hyper-immunized egg product obtained from an egg-laying animal, the present invention relates to a hyper-immune egg product comprising a therapeutically effective amount of one or more antibodies against an antigen selected from the group consisting of Enterococcus faecalis, Enterococcus faecalis cytolysin toxin, and Enterococcus faecium, for preventing or treating the alcoholic liver disease or graft versus host disease in the subject. The disclosure also relates to hyper-immunized eggs and egg products produced by animals that have been hyper-immunized with an antigen selected from the group consisting of Enterococcus faecalis, Enterococcus faecalis cytolysin toxin and Enterococcus faecium. Methods of making the hyper-immune eggs and egg products are also disclosed. 在一个方面中